Figure 7: Plots showing the influence of a 10-fold increase in YM of the cytoplasm on cell and nucleus height and width strains at 10% compression in three cell locations in the RZ: near the subchondral bone plate (Cell 1), in the middle of RZ (Cell 2), and near PZ the (Cell 3). (a) Chondrocyte height and width strain at each cell location. (b) Nucleus height and width strain for each cell location. The influence of the cytoplasm modulus on cell nucleus strain is more pronounced as the cell location approaches the PZ. Cilium strains were unchanged by the increase in cytoplasm modulus.