Table 1: Patients affected by change in risk stratification.


Female sex (n = 4) Male sex (n = 9)

Prepubertal 50% (2/4) 55% (5/9)

Low-significant risk change 50% (2/4) 0

Intermediate-high risk change 50% (2/4) 55.5% (5/9)

Low-high risk change 0 44.4% (4/9)

Diagnoses Neuroblastoma (1) Lymphoma (5)
T cell Lymphoma (1) Neuroblastoma (1)
Rhabdosarcoma (1) Osteosarcoma (2)
Osteosarcoma (1) Relapsed all (1)

Fertility preservation
Completed prior to treatment 0/4 2/9
Declined prior to treatment 3/4 2/9
Not eligible for FP prior to treatment 1/4 5/9

The patient was not eligible by prior criteria, but by new criteria, the patient would have been eligible for experimental FP protocols.