| Figure 3: Locomotor activity in the open field apparatus of mice exposed to chronic social defeat stress and ethanol administration. The test was performed for 5 min after 24 h of ethanol withdrawal. (a) Total distance traveled in the apparatus; (b) latency to enter for the first time in the center of the apparatus; (c) time spent in the center of the apparatus; (d) distance traveled in the center of the apparatus. Data are reported as mean ± SE (n = 8–9 animals per group). a, P < .05 relative to control-vehicle group; b, P < .05 relative to control-ethanol group; d, P < .05 relative to stress-ethanol group. |