Justus Liebig University Giessen
Germany

Biography

Christoph Rummel is an independent research group leader at Justus Liebig University Giessen (JLU), Gießen, Germany, and was member of the prestigious Emmy Noether Program of the German Research Foundation at the Institute of Veterinary Physiology and Biochemistry of the JLU, Germany. His group focuses on mechanisms and mediators in immune-to-brain communication pathways during infection and inflammation. Prior to taking up this position in 2008, he undertook a post doc in the "Neuroinflammation Training Program" at McGill University Montréal, Canada, from 2005 to 2007. He completed his doctoral studies in veterinary medicine at JLU in 2005.

His field of research focuses on the question of how the immune system communicates with the brain during inflammation; modulating effects of nutrition or substances that reflect the nutritional status (leptin/adipokines, obesity, omega 3 fatty acids); other modulating factors include "aging" or "psychological stress"; stimuli of the innate immune system, either bacterial (LPS), viral (polyI:C, imiquimod) or endogenous origin (IL-6, HMGB1) are tested in various rodent models (in vivo telemetry, neuroanatomy, inflammatory transcription factors, prostaglandins, cytokines).

Fields of Interest

• Cytokines
• Interleukin 6
• Leptin
• Obesity
• Inflammatory Transcription Factors
• STAT3
• NFkB
• NF-IL6
• Systemic Inflammation and Brain
• Fever
• Sepsis
• Immune-to-Brain Communication
• Hypothalamus
• Circumventricular Organs
• TLR-Agonists
• DAMPs
• Prostaglandins
• COX2
• mPGES