Simon C. F. Rawlinson
Queen Mary University of LondonUnited Kingdom
Biography
Simon Rawlinson is a senior lecturer in the Oral Bioengineering department in the Institute of Dentistry, Queen Mary University of London, UK. He was awarded his Ph.D. in 1999 from the Royal Veterinary College, London, UK. The theme of the thesis was regulation of prostaglandin release from resident bone cells in organ culture models in response to physiological loads. At this time he became interested in the apparent disparity of bone mass and mechanical usage of the skull and limb, and investigating the mechanical responsiveness of the alveolar and basal bone of the mandible, comparing the transcriptomes of the skull, limb and mandible. More recently work has concentrated on the osteogenic potential of implantable bioglasses, and use of a perfusion culture system to identify the interplay between microporosity of manufactured substrates and fluid flow to promote an osteogenic response.
He is keen to promote the view of how mechanics can modulate cellular responses. Whilst scientific endeavor has made great strides in our understanding of biological systems, the role mechanics play is largely overlooked. He was editor of ‘Mechanobiology: Exploitation for Medical Benefit’ published in 2017.
Fields of Interest
- Mechanobiology
- Bone
- 3D Cell Culture
- Regenerative Medicine
- Bioglass
- Implants
- Mechanically Adaptive Bone Remodeling
- Positional Identity
- Tissue Remodeling