Table 4: Biological activity of Schiff's base A1 and its metal complexes.


Sample and tested organism A1 Ni-A1 complex Co-A1 complex Mn-A1 complex Zn-A1 complex Hg-A1 complex CuAc-A1 complex CuSO4-A1 complex Fe-A1 complex Ce-A1 complex Cr-A1 complex Standard

Fungi Amphotericin

Aspergillus fumigates (RCMP02568) 15.7±0.33 18.7±0.36 15.3±0.55 17.6±0.58 13.6±0.25 17.3±0.44 20.2±0.55 12.6±0.25 15.7±0.36 16.8±0.39 23.7±0.10

C. albicans (RCMB02568) 13.8±0.25 16.9±0.27 13.4±0.35 15.4±0.25 11.7±0.34 16.9±0.25 19.6±0.33 11.2±0.33 13.3±0.36 15.9±0.44 25.4±0.10

Gram positive bacteria Ampicillin

Streptococcus (RCMB010010) 13.8 16.9±0.58 12.9±0.63 17.5±0.44 12.3±0.58 14.6±0.58 16.3±0.55 23.8±0.20 NA NA 16.7±0.36 23.8±0.20

Bacillus subtilis (RCMB010067) 13.1 18.2±0.44 13.2±0.58 19.8±0.63 12.7±0.37 14.3±0.58 18.3±0.25 32.4±0.30 NA NA 19.2±0.27 32.4±0.30

Gram negative bacteria Gentamicin

Pseudomonas aeruginosa (RCMB010043) 17.9 NA NA NA NA NA 18.3±0.25 17.3±0.10 NA NA NA 17.3±0.10

Escherichia coli (RCMB010052) 17.2 11.9±0.63 10.8±0.44 18.9±0.25 8.5±0.37 9.4±0.44 22.6±0.44 19.9±0.30 NA NA 13.6±0.36 19.9±0.30

A1: is benzoylhydrazone Schiff's base of IUPAC name (2(1-hydrazonoethyl) phenol); NA means no activity, data are expressed in the form of mean ± standard deviation (SD).