Table 4: Biological activity of Schiff's base A1 and its metal complexes.
Sample and tested organism | A1 | Ni-A1 complex | Co-A1 complex | Mn-A1 complex | Zn-A1 complex | Hg-A1 complex | CuAc-A1 complex | CuSO4-A1 complex | Fe-A1 complex | Ce-A1 complex | Cr-A1 complex | Standard |
Fungi | Amphotericin | |||||||||||
Aspergillus fumigates (RCMP02568) | 15.7±0.33 | 18.7±0.36 | 15.3±0.55 | 17.6±0.58 | 13.6±0.25 | 17.3±0.44 | 20.2±0.55 | 12.6±0.25 | 15.7±0.36 | 16.8±0.39 | 23.7±0.10 | |
C. albicans (RCMB02568) | 13.8±0.25 | 16.9±0.27 | 13.4±0.35 | 15.4±0.25 | 11.7±0.34 | 16.9±0.25 | 19.6±0.33 | 11.2±0.33 | 13.3±0.36 | 15.9±0.44 | 25.4±0.10 | |
Gram positive bacteria | Ampicillin | |||||||||||
Streptococcus (RCMB010010) | 13.8 | 16.9±0.58 | 12.9±0.63 | 17.5±0.44 | 12.3±0.58 | 14.6±0.58 | 16.3±0.55 | 23.8±0.20 | NA | NA | 16.7±0.36 | 23.8±0.20 |
Bacillus subtilis (RCMB010067) | 13.1 | 18.2±0.44 | 13.2±0.58 | 19.8±0.63 | 12.7±0.37 | 14.3±0.58 | 18.3±0.25 | 32.4±0.30 | NA | NA | 19.2±0.27 | 32.4±0.30 |
Gram negative bacteria | Gentamicin | |||||||||||
Pseudomonas aeruginosa (RCMB010043) | 17.9 | NA | NA | NA | NA | NA | 18.3±0.25 | 17.3±0.10 | NA | NA | NA | 17.3±0.10 |
Escherichia coli (RCMB010052) | 17.2 | 11.9±0.63 | 10.8±0.44 | 18.9±0.25 | 8.5±0.37 | 9.4±0.44 | 22.6±0.44 | 19.9±0.30 | NA | NA | 13.6±0.36 | 19.9±0.30 |
A1: is benzoylhydrazone Schiff's base of IUPAC name (2(1-hydrazonoethyl) phenol); NA means no activity, data are expressed in the form of mean ± standard deviation (SD). |